BDBM50306744 CHEMBL601221::Isopropyl 8-Fluoro-1,1-dimethyl-3-[4-(2-morpholin-4-ylethoxy)-benzoyl]-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

SMILES CC(C)OC(=O)C1=CN(CC(C)(C)c2c1[nH]c1cc(F)ccc21)C(=O)c1ccc(OCCN2CCOCC2)cc1

InChI Key InChIKey=MQJXATYHWGVGKI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306744   

TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  99nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed