BDBM50307180 5-(2,5-dimethoxyphenylthio)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL597382

SMILES COc1ccc(OC)c(Sc2c(C)[nH]c3nc(N)nc(N)c23)c1

InChI Key InChIKey=VRBQJPJAOYGKGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307180   

TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307180BDBM50307180(5-(2,5-dimethoxyphenylthio)-6-methyl-7H-pyrrolo[2,...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307180BDBM50307180(5-(2,5-dimethoxyphenylthio)-6-methyl-7H-pyrrolo[2,...)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed