BDBM50307512 CHEMBL605774::N-Benzyl-8-(cyclopentylamino)-N-hydroxy-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

SMILES Cn1nc(C(=O)N(O)Cc2ccccc2)c2CCc3cnc(NC4CCCC4)nc3-c12

InChI Key InChIKey=PYNNKMHZEUWQGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307512   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307512BDBM50307512(N-Benzyl-8-(cyclopentylamino)-N-hydroxy-1-methyl-4...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307512BDBM50307512(N-Benzyl-8-(cyclopentylamino)-N-hydroxy-1-methyl-4...)
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed