BDBM50308303 (S)-N-(2,4-Dimethylphenyl)-7-(2-(hydroxyamino)-2-oxoethoxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide hydrochloride::CHEMBL598618

SMILES Cc1ccc(NC(=O)[C@@H]2Cc3ccc(OCC(=O)NO)cc3CN2)c(C)c1

InChI Key InChIKey=ILRBNKCQNRKOPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308303   

TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50308303((S)-N-(2,4-Dimethylphenyl)-7-(2-(hydroxyamino)-2-o...)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of HDAC8 expressed in Escherichia coli assessed as Boc-Lys (acetyl)-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed