BDBM50308589 8-{[5-Chloro-2-(4-isopropylpiperazin-1-yl)isonicotinoyl]-amino}-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide::CHEMBL590961

SMILES CC(C)N1CCN(CC1)c1cc(C(=O)Nc2ccc3CCc4c(nn(c4-c3c2)-c2ccc(F)cc2)C(N)=O)c(Cl)cn1

InChI Key InChIKey=RIUYPINVLVPTAI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308589   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50308589(8-{[5-Chloro-2-(4-isopropylpiperazin-1-yl)isonicot...)Copy SMILESCopy InChI

Affinity DataIC50: 107nMAssay Description:Inhibition of human recombinant IKK2-mediated transfer of [gamma33P]ATP to biotinylated IkappaBalpha after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2010
Entry Details Article
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