BDBM50308603 1-(4-Fluorophenyl)-8-{[2-(4-methylpiperazin-1-yl)-isonicotinoyl]amino}-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide::CHEMBL591764

SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1ccc2CCc3c(nn(c3-c2c1)-c1ccc(F)cc1)C(N)=O

InChI Key InChIKey=OKDJMNVZSRNBCM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308603   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50308603(1-(4-Fluorophenyl)-8-{[2-(4-methylpiperazin-1-yl)-...)Copy SMILESCopy InChI

Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant IKK2-mediated transfer of [gamma33P]ATP to biotinylated IkappaBalpha after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2010
Entry Details Article
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