BDBM50308676 (R)-N-(4-{1-[3-(4-Trimethylsilanylbenzyl)thioureido]-ethyl}phenyl)methanesulfonamide::CHEMBL590999

SMILES C[C@@H](NC(=S)NCc1ccc(cc1)[Si](C)(C)C)c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=FWWLXAFCEUEQRU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308676   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308676((R)-N-(4-{1-[3-(4-Trimethylsilanylbenzyl)thioureid...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308676((R)-N-(4-{1-[3-(4-Trimethylsilanylbenzyl)thioureid...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed