BDBM50308861 3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethylaminomethylphenyl)-benzamide::CHEMBL590811

SMILES CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)Nc3ccc(cc3)C#N)c2)cc1

InChI Key InChIKey=BXCQIDVVQQYTNJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50308861   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed