BDBM50308871 CHEMBL599792::N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzyl]-3,4-dimethoxy-benzamide

SMILES COc1ccc(cc1OC)C(=O)NCc1cccc(c1)C(=O)Nc1ccc(CN(C)C)cc1

InChI Key InChIKey=MMRPIWYTUYGTFQ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50308871   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human ROCK2 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human CYP3A4 using BFC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP1A2 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C19 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308871(N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed