BDBM50309407 2-(2-((4'-cyanobiphenyl-2-yl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid::CHEMBL592217

SMILES OC(=O)Cc1sc(Cc2ccccc2-c2ccc(cc2)C#N)nc1-c1ccc(F)cc1

InChI Key InChIKey=WCTIFYXNSJWYEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309407   

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309407(2-(2-((4'-cyanobiphenyl-2-yl)methyl)-4-(4-fluoroph...)
Affinity DataIC50: 170nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309407(2-(2-((4'-cyanobiphenyl-2-yl)methyl)-4-(4-fluoroph...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed