BDBM50309679 (2S,6S,2R)-2-[6-(2-Acetyloxy-2-phenylethyl)-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride::CHEMBL597067

SMILES CN1[C@H](C[C@H](OC(C)=O)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1

InChI Key InChIKey=GJWRCTSARJBEEU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309679   

TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309679((2S,6S,2R)-2-[6-(2-Acetyloxy-2-phenylethyl)-1-meth...)
Affinity DataKi:  4.64E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309679((2S,6S,2R)-2-[6-(2-Acetyloxy-2-phenylethyl)-1-meth...)
Affinity DataKi:  8.05E+3nMAssay Description:Displacement of [3H]MTBZ from VMAT2 in rat whole brain vesicles by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309679((2S,6S,2R)-2-[6-(2-Acetyloxy-2-phenylethyl)-1-meth...)
Affinity DataKi:  3.14E+4nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat brain hippocampal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed