BDBM50309809 CHEMBL609611::trans-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporphine

SMILES C[C@H]1Cc2ccc3C[C@H]4N(C)CCc5cccc(c45)-c3c2O1

InChI Key InChIKey=MSFBLSXHRFJARJ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309809   

Target5-hydroxytryptamine receptor 1A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50309809(trans-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporp...)
Affinity DataIC50: 18nMAssay Description:Agonist activity at 5HT1A receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50309809(trans-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporp...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50309809(trans-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporp...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50309809(trans-N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporp...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed