BDBM50309933 6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipentyl-tetradecahydro-3a,6,9,12-tetraaza-cyclopentacyclododecen-11-yl)-hexanoic acid hydroxyamide::CHEMBL589906

SMILES CCCCC[C@H]1NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCC)NC1=O

InChI Key InChIKey=IYOLVIFIJXUYFW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309933   

TargetHistone deacetylase 4(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50: 340nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed