BDBM50310339 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-ylide 1,1-dioxide::CHEMBL605161

SMILES [O-][N+](=O)c1ccc2c(c1)S(=O)(=O)N=S2c1ccc(Br)cc1

InChI Key InChIKey=LWSWLSGAKCSXBP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50310339   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of LOX5 in human PMBL by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in insect Sf9 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of COX2 in mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human recombinant COX1 in human platelets by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50310339(3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of HER1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed