BDBM50311414 CHEMBL1078492::N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-5-(pyridin-2-yl)thiophene-2-sulfonamide

SMILES O=S(=O)(Nc1ccc2CCN(Cc3ccn[nH]3)CCc2c1)c1ccc(s1)-c1ccccn1

InChI Key InChIKey=OSRBIQHRPHNLEN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311414   

TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311414(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataEC50:  7.94nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311414(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311414(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311414(N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human ghrelin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed