BDBM50311419 CHEMBL1078464::N-(4-fluorophenyl)-5-((2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)methylsulfonyl)pyridin-2-amine

SMILES Fc1ccc(Nc2ccc(cn2)S(=O)(=O)Cc2ccc3CCNCCc3c2)cc1

InChI Key InChIKey=PAXSCWZUUPYDJA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311419   

TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311419(N-(4-fluorophenyl)-5-((2,3,4,5-tetrahydro-1H-benzo...)
Affinity DataEC50:  19.9nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311419(N-(4-fluorophenyl)-5-((2,3,4,5-tetrahydro-1H-benzo...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311419(N-(4-fluorophenyl)-5-((2,3,4,5-tetrahydro-1H-benzo...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human ghrelin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed