BDBM50311607 CHEMBL1076274::N-((1S,3S)-3-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)cyclopentyl)-3'-chlorobiphenyl-3-carboxamide

SMILES Nc1nc(=O)n(cc1F)[C@H]1CC[C@@H](C1)NC(=O)c1cccc(c1)-c1cccc(Cl)c1

InChI Key InChIKey=QEIMRMQJXBGKST-ROUUACIJSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311607   

TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311607(CHEMBL1076274 | N-((1S,3S)-3-(4-amino-5-fluoro-2-o...)
Affinity DataEC50:  180nMAssay Description:Inhibition of deoxycytidine kinase-mediated arabinoside C-induced cytotoxicityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311607(CHEMBL1076274 | N-((1S,3S)-3-(4-amino-5-fluoro-2-o...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human deoxycytidine kinase by lysate filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed