BDBM50311645 1-(9-(2,6-dichlorobenzyl)-8-oxo-8,9-dihydro-7H-purin-2-yl)-1H-benzo[d]imidazole-6-carbonitrile::CHEMBL1079524

SMILES Clc1cccc(Cl)c1Cn1c2nc(ncc2[nH]c1=O)-n1cnc2ccc(cc12)C#N

InChI Key InChIKey=GLGROCMJDUBCIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311645   

TargetTyrosine-protein kinase JAK3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311645(1-(9-(2,6-dichlorobenzyl)-8-oxo-8,9-dihydro-7H-pur...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311645(1-(9-(2,6-dichlorobenzyl)-8-oxo-8,9-dihydro-7H-pur...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed