BDBM50311646 (+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(chroman-4-yl)-7H-purin-8(9H)-one::CHEMBL1079525

SMILES O=c1[nH]c2cnc(nc2n1C1CCOc2ccccc12)-n1cnc2ccccc12

InChI Key InChIKey=IYQNSOWQLSAIBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311646   

TargetTyrosine-protein kinase JAK3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311646((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(chroman-4-yl...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311646((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(chroman-4-yl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed