BDBM50311649 (+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(6-chlorochroman-4-yl)-7H-purin-8(9H)-one::CHEMBL1076221

SMILES Clc1ccc2OCCC(c2c1)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12

InChI Key InChIKey=UEMPIQREYQXXPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311649   

TargetTyrosine-protein kinase JAK3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311649((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(6-chlorochro...)
Affinity DataIC50: 365nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311649((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(6-chlorochro...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed