BDBM50311714 4-(2-(chroman-3-yl)benzo[d]thiazol-6-yl)pyrimidin-2-amine::CHEMBL1079782

SMILES Nc1nccc(n1)-c1ccc2nc(sc2c1)C1COc2ccccc2C1

InChI Key InChIKey=WWVZNRRDWRTNIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311714   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311714(4-(2-(chroman-3-yl)benzo[d]thiazol-6-yl)pyrimidin-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311714(4-(2-(chroman-3-yl)benzo[d]thiazol-6-yl)pyrimidin-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed