BDBM50311716 2-(chroman-3-yl)-5-fluoro-6-(1H-pyrazol-4-yl)benzo[d]thiazole::CHEMBL1081173

SMILES Fc1cc2nc(sc2cc1-c1cn[nH]c1)C1COc2ccccc2C1

InChI Key InChIKey=SIQXAAIXYNABPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311716   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311716(2-(chroman-3-yl)-5-fluoro-6-(1H-pyrazol-4-yl)benzo...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311716(2-(chroman-3-yl)-5-fluoro-6-(1H-pyrazol-4-yl)benzo...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed