BDBM50311718 2-(chroman-3-yl)-4-methoxy-6-(1H-pyrazol-4-yl)benzo[d]thiazole::CHEMBL1081349

SMILES COc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1

InChI Key InChIKey=GUDYTHBWPHXZNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311718   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311718(2-(chroman-3-yl)-4-methoxy-6-(1H-pyrazol-4-yl)benz...)
Affinity DataIC50: 32nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311718(2-(chroman-3-yl)-4-methoxy-6-(1H-pyrazol-4-yl)benz...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed