BDBM50311723 CHEMBL1079919::methyl 3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)chroman-6-carboxylate

SMILES COC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1

InChI Key InChIKey=OFEDNGDWONMNKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311723   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311723(methyl 3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)...)
Affinity DataIC50: 59nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311723(methyl 3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)...)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed