BDBM50311725 CHEMBL1081193::N-(3-methoxybenzyl)-6-(1H-pyrazol-4-yl)benzo[d]thiazole-2-carboxamide

SMILES COc1cccc(CNC(=O)c2nc3ccc(cc3s2)-c2cn[nH]c2)c1

InChI Key InChIKey=QNPPKDKWSZVWSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311725   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311725(N-(3-methoxybenzyl)-6-(1H-pyrazol-4-yl)benzo[d]thi...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311725(N-(3-methoxybenzyl)-6-(1H-pyrazol-4-yl)benzo[d]thi...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed