BDBM50311727 CHEMBL1081001::N-(3-methoxybenzyl)-N-(2-methoxyethyl)-6-(1H-pyrazol-4-yl)benzo[d]thiazole-2-carboxamide

SMILES COCCN(Cc1cccc(OC)c1)C(=O)c1nc2ccc(cc2s1)-c1cn[nH]c1

InChI Key InChIKey=JOLYRRPJAITDGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311727   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311727(N-(3-methoxybenzyl)-N-(2-methoxyethyl)-6-(1H-pyraz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL
LigandPNGBDBM50311727(N-(3-methoxybenzyl)-N-(2-methoxyethyl)-6-(1H-pyraz...)
Affinity DataIC50: 871nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed