BDBM50311747 CHEMBL1080717::N-(2,6-dimethylbenzyl)-6,7-dimethylpyrrolo[1,2-a]pyrazin-1-amine

SMILES Cc1cc2c(NCc3c(C)cccc3C)nccn2c1C

InChI Key InChIKey=QWOUZMOGMXMQHZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311747   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311747(N-(2,6-dimethylbenzyl)-6,7-dimethylpyrrolo[1,2-a]p...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311747(N-(2,6-dimethylbenzyl)-6,7-dimethylpyrrolo[1,2-a]p...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311747(N-(2,6-dimethylbenzyl)-6,7-dimethylpyrrolo[1,2-a]p...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311747(N-(2,6-dimethylbenzyl)-6,7-dimethylpyrrolo[1,2-a]p...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311747(N-(2,6-dimethylbenzyl)-6,7-dimethylpyrrolo[1,2-a]p...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed