BDBM50311816 1-(4-(4-(4-(2,6-dip-tolylisonicotinoyl)piperazin-1-yl)piperidine-1-carbonyl)piperidin-1-yl)ethanone::CHEMBL1076223

SMILES CC(=O)N1CCC(CC1)C(=O)N1CCC(CC1)N1CCN(CC1)C(=O)c1cc(nc(c1)-c1ccc(C)cc1)-c1ccc(C)cc1

InChI Key InChIKey=YZIRPGUREXXEJC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311816   

TargetAcetyl-CoA carboxylase 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50311816(1-(4-(4-(4-(2,6-dip-tolylisonicotinoyl)piperazin-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of c-Myc tagged human recombinant ACC2 expressed in baculovirus infected Sf9 cell system assessed as malonyl-CoA synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50311816(1-(4-(4-(4-(2,6-dip-tolylisonicotinoyl)piperazin-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant ACC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50311816(1-(4-(4-(4-(2,6-dip-tolylisonicotinoyl)piperazin-1...)
Affinity DataIC50: 101nMAssay Description:Inhibition of c-Myc tagged human recombinant ACC1 expressed in baculovirus infected Sf9 cell system assessed as malonyl-CoA synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50311816(1-(4-(4-(4-(2,6-dip-tolylisonicotinoyl)piperazin-1...)
Affinity DataIC50: 101nMAssay Description:Inhibition of human recombinant ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed