BDBM50311967 6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine::CHEMBL1079428

SMILES Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1ccccc1

InChI Key InChIKey=NTRDNLUCOPAXFK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311967   

TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of FLtMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311967(6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Tie-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed