BDBM50311975 2-(1-isobutyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5,4-d]pyrimidin-7-amine::CHEMBL1079590

SMILES CC(C)Cn1cnc(c1-c1nc2c(N)ncnc2s1)-c1ccccc1

InChI Key InChIKey=YDDKBUNHUCXGEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311975   

TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311975(2-(1-isobutyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed