BDBM50312066 CHEMBL1081647::N-(3-(3-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2c(cnn12)-c1cnn(CCN2CCCC2)c1

InChI Key InChIKey=CNAMYLDNIIXYMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312066   

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312066(N-(3-(3-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrazol-4...)
Affinity DataIC50: 393nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed