BDBM50312148 3-(1,3-dioxoisoindolin-2-yl)-N-(2-hydroxyphenyl)benzamide::CHEMBL1080482

SMILES Oc1ccccc1NC(=O)c1cccc(c1)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=IDEZYDVMEZINTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312148   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50312148(3-(1,3-dioxoisoindolin-2-yl)-N-(2-hydroxyphenyl)be...)
Affinity DataIC50: 77nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed