BDBM50312156 1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea::CHEMBL1079850

SMILES Fc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F

InChI Key InChIKey=GHPCAIWYHJZRGR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312156   

TargetAngiopoietin-1 receptor(Human)
Cgi Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312156BDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50: 37nMAssay Description:Inhibition of Tie2 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Cgi Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312156BDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)
Affinity DataIC50: 49nMAssay Description:Inhibition of EphB4 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed