BDBM50312458 2-(4-(3-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)propoxy)-2-methylphenoxy)acetic Acid::CHEMBL1081786

SMILES COc1ccc(cc1)-c1nc(SCCCOc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC)cc1

InChI Key InChIKey=QMWAICZHSKOZJP-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312458   

TargetPeroxisome proliferator-activated receptor alpha(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312458BDBM50312458(2-(4-(3-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)...)
Affinity DataEC50:  5.25E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312458BDBM50312458(2-(4-(3-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)...)
Affinity DataEC50:  6.89E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312458BDBM50312458(2-(4-(3-(4,5-Bis(4-methoxyphenyl)thiazol-2-ylthio)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed