BDBM50312504 2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyphenyl)thiazol-2-yl)methoxy)phenyl)acetic Acid::CHEMBL1081380

SMILES COc1ccc(cc1)-c1nc(COc2ccc(CC(O)=O)cc2)sc1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=RVXJUPZVCFYIAG-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312504   

TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312504BDBM50312504(2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyp...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312504BDBM50312504(2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyp...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312504BDBM50312504(2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyp...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed