BDBM50312523 (E)-2-amino-5-(4-hydroxybenzylidene)-4,6-dimethyl-5H-cyclopenta[b]pyridine-3,7-dicarbonitrile::CHEMBL1082551

SMILES Cc1c(C#N)c(N)[nH]c2c(C#N)c(=C)c(=Cc3ccc(O)cc3)c12

InChI Key InChIKey=LCZYDPXLMLXHLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312523   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50312523((E)-2-amino-5-(4-hydroxybenzylidene)-4,6-dimethyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of "N-terminal GST-tagged human B-Raf assessed as luminescence activity after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed