BDBM50312623 CHEMBL1076939::Octanedioic Acid-{3-[1-(3-Fluoro-4-methoxyphenyl)-1H-[1,2,3]-triazol-4-yl]phenyl}amide-Hydroxyamide

SMILES COc1cc(ccc1F)-n1cc(nn1)-c1cccc(NC(=O)CCCCCCC(=O)NO)c1

InChI Key InChIKey=MAMVMWHNRXWFPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312623   

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312623(Octanedioic Acid-{3-[1-(3-Fluoro-4-methoxyphenyl)-...)
Affinity DataIC50: 3.39nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312623(Octanedioic Acid-{3-[1-(3-Fluoro-4-methoxyphenyl)-...)
Affinity DataIC50: 3.85nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312623(Octanedioic Acid-{3-[1-(3-Fluoro-4-methoxyphenyl)-...)
Affinity DataIC50: 5.06nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed