BDBM50312744 (S)-N1-(5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-(3-(trifluoromethyl)phenyl)propane-1,2-diamine::CHEMBL1080561

SMILES Cc1n[nH]c2ccc(cc12)-c1nnc(NC[C@@H](N)Cc2cccc(c2)C(F)(F)F)s1

InChI Key InChIKey=GGQSOEXSCZITMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312744   

LigandPNGBDBM50312744((S)-N1-(5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadia...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of AKT1 after 10 mins by [gamma33]ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50312744((S)-N1-(5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadia...)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed