BDBM50312749 (S)-N1-(5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-(4-chlorophenyl)propane-1,2-diamine::CHEMBL1081451

SMILES N[C@H](CNc1nnc(s1)-c1ccc2[nH]ncc2c1)Cc1ccc(Cl)cc1

InChI Key InChIKey=NHCKWRFRGQYSQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312749   

LigandPNGBDBM50312749((S)-N1-(5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: 24nMAssay Description:Inhibition of AKT1 after 10 mins by [gamma33]ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50312749((S)-N1-(5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: 41nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed