BDBM50313004 3-(6-fluoro-1-methyl-1H-indol-3-yl)-4-(3-methoxyphenyl)-1H-pyrrole-2,5-dione::CHEMBL1081616

SMILES COc1cccc(c1)C1=C(C(=O)NC1=O)c1cn(C)c2cc(F)ccc12

InChI Key InChIKey=ARSCWVMYFYXWGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313004   

TargetGlycogen synthase kinase-3 beta(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313004(3-(6-fluoro-1-methyl-1H-indol-3-yl)-4-(3-methoxyph...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313004(3-(6-fluoro-1-methyl-1H-indol-3-yl)-4-(3-methoxyph...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed