BDBM50313165 (S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydroxyphenyl)methanone::CHEMBL1080153

SMILES Oc1ccccc1C(=O)C1=CCCN2CCC[C@@H]12

InChI Key InChIKey=HOBPPDCRYVOZBO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313165   

TargetMu-type opioid receptor(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50313165((S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydro...)
Affinity DataKi:  4.90E+4nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50313165((S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydro...)
Affinity DataKi:  8.30E+4nMAssay Description:Displacement of [3H]U69593 from rat kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50313165((S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydro...)
Affinity DataKi: >2.00E+5nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed