BDBM50313370 (6S,7R,8R,9S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2,5-dioxaspiro[3.5]nonane-7,8,9-triol::CHEMBL1091476

SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC3(COC3)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=FRZZZSBXSMTOTQ-CGXNFDGLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313370   

TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313370((6S,7R,8R,9S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313370((6S,7R,8R,9S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed