BDBM50313803 (1R,3S)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzylamino)-1-phenylbutan-2-yl)-3-(2-propionamidopropan-2-yl)cyclohexanecarboxamide::CHEMBL1084432

SMILES CCC(=O)NC(C)(C)[C@H]1CCC[C@H](C1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CNCc1cccc(c1)C(C)C

InChI Key InChIKey=PCVULHPMCAPMCJ-RYTSNQFKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313803   

TargetBeta-secretase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50313803((1R,3S)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzyla...)
Affinity DataIC50:  580nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50313803((1R,3S)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzyla...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50313803((1R,3S)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzyla...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed