BDBM50314198 (+/-)-1-(4-(2-(5-(1-(2-hydroxy-3-(piperidin-1-yl)propyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-2-(trifluoromethyl)phenylthio)ethyl)piperazin-1-yl)ethanone::CHEMBL1089293

SMILES CC(=O)N1CCN(CCSc2cc(ccc2C(F)(F)F)-c2nn(CC(O)CN3CCCCC3)c3CCN(Cc23)S(C)(=O)=O)CC1

InChI Key InChIKey=ICPBGKIKHDNXQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314198   

TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314198((+/-)-1-(4-(2-(5-(1-(2-hydroxy-3-(piperidin-1-yl)p...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human cathepsin S by ADAM-28 substrate-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed