BDBM50314344 4-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)methyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(2-hydroxyethyl)benzamide::CHEMBL1092754
SMILES Cn1cc(\C=C2/Oc3cccc(O)c3C2=O)c2c(ccnc12)-c1ccc(cc1)C(=O)NCCO
InChI Key InChIKey=YDELNSXADYPQGS-BKUYFWCQSA-N
Data 21 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50314344
Affinity DataIC50: 50nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GCKMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of P38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of cMetMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair