BDBM50314447 (S)-N-((S)-3,3-dimethyl-1-((S)-2-(4-(naphthalen-1-yl)thiazol-2-yl)pyrrolidin-1-yl)-1-oxobutan-2-yl)-2-(methylamino)propanamide::CHEMBL1091762

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(cs1)-c1cccc2ccccc12)C(C)(C)C

InChI Key InChIKey=GYYAJGUBSPVKPD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314447   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50314447((S)-N-((S)-3,3-dimethyl-1-((S)-2-(4-(naphthalen-1-...)
Affinity DataKi:  6.80E+4nMAssay Description:Antagonist activity at XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 7(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50314447((S)-N-((S)-3,3-dimethyl-1-((S)-2-(4-(naphthalen-1-...)
Affinity DataKi:  2.20E+5nMAssay Description:Antagonist activity at ML-IAP MLXBIR3SG domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed