BDBM50314616 (S)-N-(4-(cyclohexylmethoxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide::CHEMBL1093699

SMILES COc1cc(OCC2CCCCC2)c(F)cc1CNC(=O)[C@@H]1CCCN1

InChI Key InChIKey=XVMROVYEPAQHAE-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50314616   

Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314616((S)-N-(4-(cyclohexylmethoxy)-5-fluoro-2-methoxyben...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314616((S)-N-(4-(cyclohexylmethoxy)-5-fluoro-2-methoxyben...)
Affinity DataEC50:  4.97nMAssay Description:Agonist activity at 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314616((S)-N-(4-(cyclohexylmethoxy)-5-fluoro-2-methoxyben...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314616((S)-N-(4-(cyclohexylmethoxy)-5-fluoro-2-methoxyben...)
Affinity DataEC50:  4.03E+3nMAssay Description:Agonist activity at 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed