BDBM50314636 (E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)piperidin-1-ylmethyl]phenyl}acrylamide::CHEMBL1094041

SMILES ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c([nH]c3ccccc23)-c2ccccc2)cc1

InChI Key InChIKey=OSLCXRHTDASFII-WUKNDPDISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314636   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314636((E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50314636((E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  6nMAssay Description:Inhibition of GST-tagged HDAC1 (unknown origin) expressed in insect cells using poly (Glu, Tyr) 4:1 as substrate measured after 15 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50314636((E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)pipe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed