BDBM50314701 (R)-2-(2-naphthamido)-5-(3-fluorophenyl)pent-4-ynoic acid::CHEMBL1090379

SMILES OC(=O)[C@@H](CC#Cc1cccc(F)c1)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=SHNQBRZGFPIJRJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314701   

LigandPNGBDBM50314701((R)-2-(2-naphthamido)-5-(3-fluorophenyl)pent-4-yno...)
Affinity DataKi:  1.87E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314701((R)-2-(2-naphthamido)-5-(3-fluorophenyl)pent-4-yno...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Pin1 by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed