BDBM50314702 (R)-2-(2-naphthamido)-5-(2-hydroxyphenyl)pent-4-ynoic acid::CHEMBL1090380

SMILES OC(=O)[C@@H](CC#Cc1ccccc1O)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=JWOVEMHKPOPVIR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314702   

LigandPNGBDBM50314702((R)-2-(2-naphthamido)-5-(2-hydroxyphenyl)pent-4-yn...)
Affinity DataKi:  4.43E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314702((R)-2-(2-naphthamido)-5-(2-hydroxyphenyl)pent-4-yn...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Pin1 by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed